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University receives recognition for its high number of patent requests filed

University receives recognition for its high number of patent requests filed

  • The National Institute of Industrial Property recognized Universidad de Santiago as the third Chilean university with the highest number of invention patent requests that seek to contribute to the country development in fields like chemistry and biology, engineering and technology. Maximiliano Santa Cruz, Inapi’s National Director and Óscar Bustos, Vice President of Research, Development and Innovation of Universidad de Santiago,   encouraged the University community to continue constantly producing industrial innovations to contribute to society.

On April 25th, in the context of the World Intellectual Property Day, our University was recognized as the third best national institution in requesting invention patents during 2013.

The National Institute of Industrial Property (Inapi, in Spanish)- an agency responsible to the Ministry of Economy in charge of registering, managing and promoting industrial property rights in Chile- granted our University an award in a ceremony led by Maximiliano Santa Cruz, Inapi´s National Director.

During the activity that took place at Inapi’s building, Santa Cruz highlighted the important role played by our University in producing creative innovations that contribute to our country’s development.

“Universidad de Santiago de Chile is absolutely essential to our patenting system. It has always been in the highest positions at the patent request ranking and this is not a coincidence: it is the result of serious intellectual property policies,” Inapi’s director said.

For Maximiliano Santa Cruz, our University’s interest in industrial property “is a powerful signal to its researchers, professors and innovators, in general.”

“I ask Universidad de Santiago’s innovators to continue creating new things and using the patenting system for it is a powerful tool to protect intellectual property,” he added.

Dr. Óscar Bustos, Vice President of Research, Development and Innovation (Vridei, in Spanish) of our University, who received Inapi´s award, showed himself very pleased with the position in the ranking at a national level.

“We are very satisfied with our exceptional position among the institutions that request for invention patents (…) We would have been happy to keep the second place like we did last year, but being among the main institutions that file patents requests in Chile is excellent news indeed,” Dr. Bustos said.

Pontifica Universidad Católica was at the first place in the patent request ranking while Universidad de Concepción was at the second place.

Finally, Vice President Bustos said that the high position of our University in the ranking reflects that “our researchers have become aware that not only scientific publications are important for our country: developing specific technological projects in key areas for Chile is important too.”

According to data provided by the Department of Technology Transfer of our University, during 2013, this state and public institution filed 11 invention patent requests in Chile, and at the same time, it filed other 42 requests with foreign agencies in charge of registering industrial inventions.

Translated by Marcela Contreras
 

International Scientific Journal dedicates special issue to researcher at Universidad de Santiago

International Scientific Journal dedicates special issue to researcher at Universidad de Santiago

  • The renowned Journal of Coordination Chemistry dedicated its issue 67 to Dr. Juan Costamagna, academic at the Faculty of Chemistry and Biology of Universidad de Santiago, for his contribution to the development of this journal since 2000, when he was invited to be part of the Editorial Board. The journal aims at disseminating the investigations of renowned researchers in the field of Chemistry of Coordination Compounds in countries like the United States, France, Argentina, South Africa, and Chile, among others. 

 


In recognition of his significant contributions to the development of the Journal of Coordination Chemistry and in the context of his retirement from the Editorial Board, the journal dedicated a special issue to Dr. Juan Costamagna, researcher at the Faculty of Chemistry and Biology of Universidad de Santiago.

The journal aims at disseminating the investigations of renowned researchers in the field of Chemistry of Coordination Compounds in countries like the United States, France, Argentina, Uruguay, South Africa, Spain, Italy, Mexico, and Chile.

Jim Atwood, who was in charge of issue 67 called “Special Issue: To honor Professor Juan Costamagna on the occasion of his retirement", highlighted in the opening pages professor Costamagna’s “valuable opinion” and his contribution over the years “with his expertise” to the development of this publication.

Atwood pointed out that Dr. Costamagna “has been a consummate collaborator and has brought his talent to the Editorial Board of this Journal; he has published over 100 papers in the field of Coordination Chemistry and has served 14 times as the Chilean delegate to the International Advisory Committee of the International Conference on Coordination Chemistry between 1974 and 2006. He was also an Advisor to the Nobel Prize of Chemistry from 1996 to 2000”. This is the background for this special issue available since December on http://www.tandfonline.com/toc/gcoo20/67/23-24.
 

Contribution to Science

The participation of Dr. Costamagna in the journal dates back to 2000, when he was appointed to the Editorial Board by the journal’s general editor.

Since then, Dr. Costamagna has contributed with countless academic evaluations and several plenary “Online Annual Meetings” of the Editorial Board. The journal has positioned itself as a model in the field of Chemistry of Coordination Compounds. “I think I have modestly contributed to this growth and development,” Dr. Costamagna said.

Regarding his plans in the editorial work, Dr. Costamagna said that he will continue working as emeritus editor for “Communications in Inorganic Synthesis”, an online journal sponsored by Universidad de Santiago.


Translated by Marcela Contreras

Reading comprehension in Chileans will be assessed through eye movement

Reading comprehension in Chileans will be assessed through eye movement

  • Researchers at Universidad de Santiago, in partnership with researchers at the University of California (USA), developed a software program that includes several applications to study reading comprehension in users of digital texts. They will analyze the reading tracks in students and professionals all over the country to understand the cognitive processes developed when approaching a text on screen.

 

New technologies have also had an impact on people’s reading habits, as a result of the widespread use of digital texts. However, according to different studies, this change has not improved reading comprehension in Chilean people.  Thus, researchers at Universidad de Santiago have developed a software program that includes several applications to study reading comprehension in users of this type of text.

“Reading comprehension is essential to any field of knowledge. If someone does not have a good reading comprehension level, it will be more difficult for him/her to understand science, mathematics and texts related to financial products or a contract, for example. For this reason, we designed computerized environments for users to develop information processing strategies that allow them to process this information in a way that eases their understanding,” Dr Héctor Ponce, professor at the Department of Accounting and Auditing and an expert in information systems, said.

To design these environments, Dr Ponce and other professors at Universidad de Santiago have developed several software applications to improve reading comprehension of digital texts by including information processing strategies, like note-taking, cause-effect diagrams, sequences and comparisons. These strategies were turned into applications that complement each other, proving the effectiveness of this technology.

The results encouraged researchers to conduct further research on how Chilean people read and understand. They are currently working on the Regular Fondecyt Project (1151092) “Facilitation of cognitive processes by means of different computer-aided information processing strategies: An eye movement analysis.”

“Although we process information in different ways, there area some repeated patterns that we are trying to identify through this study. This why we will asses the cognitive strategies that a person uses when reading,” the researcher explained.

“For this purpose, we will use a computer-connected device called ‘eye-tracker’. It detects where on the screen the user is looking at, it follows the eye movement and detects how long someone spends watching objective elements, like words, for example, or the eye movement track when processing a text, among other aspects,” he added.

To inquire into how strategies help in understanding a text, tests will be run with plain texts without strategies, and with other texts that involve individual and multiple strategies.

The research team includes experts in cognitive psychology, like Dr Verónica Figueroa, co-investigator and researcher at Universidad de Santiago, and Dr Richard Mayer, professor at the University of California (Santa Barbara), who is collaborating in the study.

The project implementation started in March this year and it will involve school and university students and professionals. The study is divided in three phases: first, the design of the material to be used; then, testing and data collection through the eye-tracking device; and finally, the analysis of the collected data.

According to Dr Ponce, the results of the study could have two potential impacts. One is the software improvement, as the most effective strategies could be assembled to understand what is being read. And the other, the possibility of improving the content presentation in textbooks and the presentation of specialized information, like the one related to online products sales, health care plans, and contracts, among others.

“In a society, it is very important for people to be able to understand what they read, as one of the natural consequences of a good comprehension is a better decision-making,” Dr Ponce stressed.

Translated by Marcela Contreras

Researchers develop a tool to assess environmental quality of urban settings

Researchers develop a tool to assess environmental quality of urban settings

  • In large cities like Santiago, the quality of life is strongly related to the quality of the environment of the urban settings we live in. This is the core idea of the study “Socio-ecological quality in urban settings: improvements for a human-scale sustainable environment. Municipality of Quinta Normal,” a Dicyt project developed by Dr Alexandre Carbonnel and Rodrigo Martin, both professors at the School of Architecture of Universidad de Santiago. The study seeks to provide a tool for assessing the quality of urban life, considering environmental conditions (thermal, acoustic, and atmospheric ones) at urban settings.

     

    “Socio-ecological quality in urban settings: improvements for a human-scale sustainable environment. Municipality of Quinta Normal,” is the name of the study conducted by Dr Alexandre Carbonnel and Rodrigo Martin, both professors at the School of Architecture of Universidad de Santiago. The project has been funded by the university’s Scientific and Technological Research Department (Dicyt, in Spanish) and it has the purpose of providing a tool for measuring the quality of urban life, considering environmental conditions (thermal, acoustic, and atmospheric ones) at urban settings.

    The first measurements will be done at the municipality of Quinta Normal, an area of the capital of 12.4 square kilometers wide, with a population of 105 thousand people, according to the national census of 2002.

    This municipality is significant for the study, as it displays several special characteristics: In spite of being close to Santiago Centro, it has several industries; it adjoins Quinta Normal Park, one of the largest green areas of the capital managed by the Municipality of Santiago; and it is traversed by some of the busiest streets of the city, like Matucana, Costanera Norte Highway, Avenida San Pablo, and Central Highway (General Velásquez).

    The first hurdle to be cleared was to define the study areas. For this purpose, the research team developed “a methodology to identify the use of the urban setting as of the use of transportation and schools, what will allow pinpointing the nodes of very intense use and measure their environmental quality,” Carbonnel said.

    In order to relate the urban environmental quality to the use of urban infrastructure and services, variables and indicators related to transportation, health care and education coverage, cultural and commercial spots, green areas, and others, will be analyzed. The researchers will use some software programs (QGis and Grasshopper3d) to cross-check the information and identify the places with higher people density and more use of space.

    Once they know the places with higher density and more use, they will measure the urban environmental quality. This process will be based on thermal, acoustic and atmospheric variables, providing a true and varied environmental record of the places to be studied 

    Study impact

    According to Dr Carbonnel, the study impact is aimed at “providing municipalities, regional governments and the community with an important information tool that includes environmental indicators to orient them at managing and making local public policies and to contribute to a better use of the funds invested in infrastructure.”

    Dr Carbonnel also said that this methodology will open doors to the creation of a new line of products. “These innovations should aim to democratizing environmental information, in agreement with the vision of the Smart City Lab research center of our university.” Both researcher work at this center, together with other professionals of the School of Psychology and the Departments of Industrial Engineering, Geographic Engineering, Electric Engineering and Computer Engineering.

    Translated by Marcela Contreras

Universidad de Santiago opens new research building

Universidad de Santiago opens new research building

  • With a space of 2,755 m2, the five-floored building will be home to the Center for the Development of Nanoscience and Nanotechnology, the Aquaculture Biotechnology Center and the Soft Matter Center. The cost of the building construction amounted to about CLP 5,000 million.

 

 

In a context in which Chile only invests 0.39 of its GDP in research, the President of Universidad de Santiago de Chile, Dr Juan Manuel Zolezzi, highlighted the importance of this new space that will contribute to research and development in the country.

“This is one of the state-of-the arts buildings in Chile with regard to university research and it is an incentive for new researchers to continue innovating in key areas for the development of Chile,” he said. He added that Universidad de Santiago de Chile is a leader in technology transfer.

Senator Guido Girardi, who heads the Challenges for the Future. Science, Technology and Innovation Commission of the Upper House, valued the work done by public universities.

“These universities take charge of basic sciences on their own. Particularly, Universidad de Santiago has had the wisdom to connect basic sciences to the problems of the country and to generate innovation to solve these problems,” he said.

A few months ago, Dr Girardi visited the Center for the Development of Nanoscience and Nanotechnology (Cedenna, in Spanish) where he met with professionals in this significant research field. After the opening ceremony he congratulated the university on the new facilities.

The centers

Representatives of the centers that will occupy the new facilities expressed their satisfaction with the architectural configuration of the building that facilitates research development.

Dr Francisco Melo, Head of the Soft Matter Center that gathers together scientists in the fields of Physics, Chemistry, Biology and Engineering, said that the new space will offer endless opportunities for a better science development and for positioning the university at an international level.

For her part, Dr Dora Altbir, Head of the Cedenna, said that the possibility of bringing together scientists from different fields will allow a more active collaboration than the one that the university has now.

Eugenio Spencer Ossa, Head of the Aquaculture Biotechnology Center (CBA, in Spanish) said that the new building will allow to further scientific research and contribute to improve domestic industrial production, like salmon farming.

Architecture

The Rector Eduardo Morales Santos Research Building, with a total surface of 2,755.15 m2, is located in the central campus of the university. Its design is a geometric reinterpretation of the heritage buildings of the institution designed by the architects Héctor Valdés, Fernando Castillo Velasco, Carlos García Huidobro and Carlos Bresciani and built between 1957 and 1967. The building’s name is a tribute to the first democratically-elected university president after the dictatorship.

 

Translated by Marcela Contreras

Plant biostimulant and fertilizer developed by students at Universidad de Santiago succeeds in the international market

Plant biostimulant and fertilizer developed by students at Universidad de Santiago succeeds in the international market

  • After the success of Nutrisato- an innovative natural fertilizer that increases by 50% the size of fruits, vegetables and plants- in the international market, its creators opened an agricultural additives company.

 

 

In his search for environmentally friendly biotechnological solutions, Alejandro Muñoz, biochemist and student at the Biotechnology doctoral program of the Faculty of Chemistry and Biology of Universidad de Santiago, developed an interesting plant biostimulant based on organic molecules which is able to increase fruits, vegetables and flowers twice their size in the same period of time.

Later, Carla Céspedes, an agronomist from Universidad de Chile, and Rodrigo Ferreira, student at the Commercial Engineering program of the Faculty of Administration and Economics of Universidad de Santiago de Chile, joined the project team and took the responsibility of placing the product in the agricultural market.

After the positive outcomes of testing Nutrisato in peppers and tomatoes, the students participated in the Brain Chile program contest and won the first place. They used the funds that they were awarded to continue developing the product to a level that they never expected: today, they have their own company called Ingeniería y Biotecnología Limitada, Atama Biotech Ltda.

Nutrisato in the market

After the Brain Chile Contest, they continued testing Nutrisato. They found that it was harmless to people and the environment and it also “doubled the size of the products, increased the production of fruits by 50% and the production of biomass in vegetables by 30%,” Alejandro Muñoz explained.

Carla Céspedes, who is responsible for the agronomic development of Nutrisato, explained: “The first products in which we tested the biostimulant were harvested in April, but after the contest, they were left abandoned in an area with Andean climate. In that context, we realized that the fertilizer reduced the cold stress in plants and enhanced their hygroscopic properties.”

Supported by recent tests, the researchers confirmed that the fertilizer worked in every product in which they used it, like spinach, celery, parsley, coriander, tomatoes, peppers, onions, cherry tomatoes and ornamental plants like tulips, roses and daisies.

Now they are testing the product in hydroponic lettuces and tomatoes, and in berries and citrus fruits, in Valdivia.

With regard to the marketing of the product, Rodrigo Ferreira, who is in charge of the company’s management and sales, says that they created Nutrisato Hogar, a product which is targeted at people who grow their own vegetables in home gardens. The product will be in the market soon.

The researchers say that they have enjoyed their work with Nustrisato, because they are doing what they like to do. For this reason, they have continued developing innovative products, like Raizato. “Raizato is a super soil enhancer that adds organic matter to the soil and enhances the growth of roots and leaves,” Alejandro Muñoz said.

Translated by Marcela Contreras

Academic creates active eco packaging to increase the useful life of berries

Academic creates active eco packaging to increase the useful life of berries

  • In the Southern Hemisphere, Chile is the largest exporter of berries. Therefore, national researchers focus their efforts on increasing their life, to allow these products to reach more distant markets. An eco active container which aims to contribute to this purpose has been generated at U. Santiago.

In 2008, Dr. Maria Paula Junqueira, academic at the Technological Faculty, committed herself  to making a contribution to the food area, and she was part of  the task of converting Chile into a food power. Thus, through a Fondef project, she tried to combat the limitations generated, particularly by the fungus Botrytis cinerea, in the so -called  berries, and this allowed their  extension of life.

The closing of the investigation "Life extension of fresh berries by using eco-active packaging” was held on Friday 19th at the Plaza San Francisco Hotel, where the results were presented to the participating institutions.

The eco active container has an antifungal agent in his film, which fights the fungus specifically mentioned. Also, it  is also friendly with the environment, because it is recyclable. To verify the efficiency of the invention, tests with raspberries and blueberries were tested in Chile, while in England raspberries and blackberries were used, because we are in different seasons.

Of all the berries used in the study, raspberries showed a better response to interact with the packaging, and this helped to extend its life in two days.

"We had a very promising result," the academic at the Department of Science and Food Technology remarked; she  added that "due to the final results of this research, an  initiative was taken in order to try with other fruits like grapes and strawberries and we already have companies which are interested in participating. "

Dr. Junqueira thanked the cooperation of the school, saying that she had "an unconditional support from the University from the start and then at all stages involved in  the project."

This work, which also involved Dr. Maria Angelica Bargains and Dr. Francisco Rodriguez, members of the same academic unit, gave birth to a patent application in Chile, which will also be replicated abroad soon.

Companies’ experience

In the presentation of results, representatives of the participating companies  were present. Enrique Harvgreaves attended in representation of  Typack company, a packaging  company. He said: "I do hope that this product is on the market soon.” He also thanked the opportunity to develop a collaborative work with the University.

Meanwhile, Alvaro Acevedo, from Vitalberry, referred to the contribution generated in the production process of these fruits during the investigation. "The market demands have pushed us to the improvement of production processes, and this has increased the quality requirements demanded for these products," he said. He also emphasized that this result "has a lot of potential; undoubtedly, it is a product to be applied massively".

Dr. Luis Magne, Head of Technology Transfer, attended on behalf of the Vice-President for Research, Development and Innovation. He said "we take on the challenge of leading the University on the path of innovation. The road has not been easy but  maturity has been achieved in the sense of understanding what technological research is. "

Luisa Martínez, financial analyst of the Fund for the Promotion of Science and Technology was also present in this event.

 By Valeria Osorio

Unprecedented images of southern night sky captured by Engineering Physics students

Unprecedented images of southern night sky captured by Engineering Physics students

  • The Optics and Photonics Group of Universidad de Santiago, led by graduate student Pablo Fredes, organized an educational astrophotography camp aiming to promote knowledge on how to handle different state-of-the-art technologies to observe the stellar panorama, capturing unprecedented photographs.

About 15 students of the Engineering Physics program participated at the First Southern Night Skies Astrophotography Camp organized by the Optics and Photonics Group of our University, which is one of the Student Chapters of the Optical Society of America (OSA).

During two nights, the young group made up of undergraduate and graduate students of the Engineering Physics program participated in the activity that was sponsored by Centro Cultural de Astronomía La Cisterna. They were taken to Observatorio Turístico y Educativo Roan Jasé, at Cajón del Maipo to become familiar with observational field work using different telescopes and high-resolution CCD cameras that operate together with a computer to capture images of the night sky.

About 15 students, together with five members of Centro Cultural de Astronomía La Cisterna, had the possibility of observing the surface of the sun and its spots during the day and enjoyed interesting talks about the life cycle of stars, constellations, exoplanets, the Mapuche world view and astrobiology, among others.

“We learned so much: setting the telescopes in ‘station’, understanding the use of mirrors and lenses, distinguishing different types of telescopes and finding celestial bodies in the sky. Watching planets directly is amazing,” the student Daniel Barrientos said. He considered the experience to be rewarding, even from a spiritual point of view.

For these young students, this approach to astronomy also represents a view to the wide variety of employment opportunities related to their program and it allows them to start exploring the possibility of working in any of the important astronomical observatories in our country.

Astronomy at Universidad de Santiago

Pablo Fredes, president of the Optics and Photonics Group of our University, one of the OSA’s Student Chapters, is also a professor at the Department of Physics and is writing his dissertation to complete his Philosophy of Science graduate program. From his experience as a teacher, he thinks that astronomy is a field that could be strengthened by our University, especially because of the relations fostered by the Planetarium and the enthusiasm shown by the students of his Department.

“All physics students are interested in astronomy,” he said, considering the advantages offered by the skies of our country for this activity and for research. “Maybe this camp can contribute to develop this field at the University,” Fredes added.

He explained that the camp idea was born last year, when the members of the group were thinking thought about the activity that they wanted hold in 2014 with funds provided by the OSA.

The OSA, through its student chapters, funds activities aiming to spread, promote and encourage studying some physics branches, like optics and photonics (the study of photons’ properties and flux).

“The OSA’s grant allowed us to buy a CCD camera- that we attached to a telescope- and to cover transportation, food and entry-fee expenses,” Fredes said.

The activity was organized together with Centro Cultural de Astronomía La Cisterna, which members are astronomy amateurs willing to share their knowledge and equipment.

“We are very happy with the results, because the activity included young people who knew much about optics but who had not had the chance of watching through a telescope or taking photographs with this type of instruments. Besides, the images we were able to capture are a valuable material, so we are doubly satisfied,” Manuel Tobar, a member of Centro Cultural de Astronomía La Cisterna, said.

In October, the members of the group are planning to hold the Second National Congress of Optics and Photonics, where they expect to exhibit the photographs taken during the camp that took place on April 4-6.

“We would like to have more activities, establish more links and have the possibility of applying for other grants, maybe at a university or at a national level,” Fredes concluded.

Translated by Marcela Contreras

Food supplement developed to prevent cancer

Food supplement developed to prevent cancer

  • “Broccoli’s myrosinase enzyme production and encapsulation for its use as a food supplement” That is the name of the Fondef project recently awarded to Alejandro Angulo, a graduate of Universidad de Santiago. In the VIU line (Valorización de la Investigación en la Universidad, in Spanish), the funds will allow to develop a capsule to prevent different cancers.

 

It is well known that eating vegetables provides many health benefits; even more: some of them have disease preventive properties. Like broccoli, for example, that according to different studies, can be a natural anticancer agent.

Based on this idea, Alejandro Angulo, Biotechnology Engineer graduated from Universidad de Santiago, submitted the project “Broccoli’s myrosinase enzyme production and encapsulation for its use as a food supplement” to the IV VIU Contest of Fondef (Fund for the Promotion of Scientific and Technological Development) and he was recently awarded the funds. The initiative has the purpose of developing a capsule to enhance the natural ability of the broccoli to prevent different cancers.

Alejandro Angulo, director of the project, explains that this vegetable is able to produce some antioxidant and anticancer compounds called isothiocyanates, like sulforphane, that is highly powerful. The precursor to this compound, the myrosinase enzyme, is found in broccoli. When you chew it, its tissue breaks down, the enzyme and the substrate react and sulforphane is naturally released. “If we have more optimal or high-activity enzymes, we could maximize the content of these anticancer compounds,” the researcher said.

For the above, he proposes to create a capsule containing purified enzyme that, when eaten with broccoli, increases the sulforphane content in the body, and therefore, its anticancer effect. However, the researcher warns that the product “would allow preventing cancer, but it would not be a treatment for cancer.”

The researcher says that the idea of developing this food supplement arose when he was looking for a topic for his dissertation work and contacted Dr. Andrea Mahn. She was working on a Fondecyt project that sought to transform broccoli into a functional food. “I focused on the broccoli enzyme that acts as a catalyst for the chemical reaction that releases the anticancer compound, and aspect that she was not studying. In my dissertation work I was trying to describe this enzyme to then purify it and leave it ready to be used in the product. It was then when we thought of developing a food supplement,” he remembers.

His idea was one of the 12 proposals submitted by Universidad de Santiago that won the last VIU Contest version, a historical record that ranks our University in the first place this year. The study will have the support of the Department of Technology Transfer (DGT, in Spanish) to move forward to the ultimate goal: to develop the product for market.

The project is at its first stage that includes a business plan and a work plan; then it will be evaluated to continue to the second stage: the project implementation. “In the long term, we expect to meet all the project stages and position the product as a recognized brand. The idea is to position the brand and sell our product,” the researcher concluded.

Translated by Marcela Contreras

Researchers propose new index of cerebral blood flow autoregulation

Researchers propose new index of cerebral blood flow autoregulation

  • A new index is the result of the study conducted by a research team at the Department of Informatics Engineering of Universidad de Santiago, led by Dr Max Chacón. This may be a great contribution to improve early detection and measurement of neurodegenerative diseases, like amyothrophic lateral sclerosis, Alzheimer’s disease, Parkinson’s disease and other alterations in cerebral hemodynamics, including cerebrovascular accidents, and subarachnoid hemorrhages, among others.

 

Cerebral autoregulation is a mechanism which aims to maintain stable cerebral blood flow, despite of the changes in blood pressure.

In order to measure this mechanism, the Aaslid Tiecks method is widely used, but it is not accurate and sometimes it provides false positives that make difficult to differentiate between healthy and sick subjects.

During the study conducted by academics of our University in partnership with the Department of Cardiovascular Sciences at the University of Leicester (United Kingdom), when the new model was applied to 16 healthy men, promising results were observed. 

This new index uses two parameters that are obtained directly from the response signal of the brain to a decrease in arterial blood pressure caused by the sudden release of bilateral thigh cuffs, and a third parameter that measures the difference between the gradient of this response and the change in arterial blood pressure.

“This new index means an improvement in the whole system. The former index did not allow differentiating between healthy and sick individuals in a correct way. When you see the results of the tests, there is an improvement in the evaluation of healthy subjects. The next challenge is to test the index in pathological cases, to confirm the results already obtained,” Dr Chacón said.

University support

Professor Chacón stressed that the study was “completely conducted at the university.” He also highlighted the support that they received from Universidad de Santiago, as the study was brought forth thanks to the contribution of the Department of Scientific and Technological Research and the Department of Informatics Engineering.

Besides, professor Chacón expressed his gratitude to his work team, made up of Dr José Luis Lara, co-author of the study and professor at the Department of Informatics Engineering, and Dr Ronney Panerai, also co-author of this work and professor at the University of Leicester. The researcher also thanked Dr Gonzalo Acuña and Dr Millaray Curilem, both professors at Universidad de la Frontera, who did not formally take part in the study, but contributed to make this research a reality.

Publication of paper

The study results were published in the paper ‘A new model-free index on dynamic cerebral blood flow autoregulation’, where the new index is proposed. It represents a breakthrough in medicine.

The paper was also published by Plos one, one of the most important scientific journals around the world. According to Dr Chacón, this journal is one of the fastest means to publish, so it provides a way to disseminate the results of his work.

He explained that his work “should have a big impact because it is a useful tool at the service of medicine. As it is useful and shows concrete results, the paper might be cited in several occasions.”

Translated by Marcela Contreras

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